UNIVERSITY OF BUCHAREST
FACULTY OF PHYSICS

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2022-07-01 16:22

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Conference: Bucharest University Faculty of Physics 2019 Meeting


Section: Nuclear and Elementary Particles Physics


Title:
Morphological properties of the chondroitin sulfate hydrogels


Authors:
Chivuța-Ramona BĂDIȚA (1, 2), Dorina ARANGHEL(1), Paul MEREUŢĂ (1), Oana GÂZĂ (1, 3)


*
Affiliation:
1) National Institute for Nuclear Physics and Engineering, Reactorului 30, RO-077125, POB-MG6 Bucharest-Magurele, Romania

2) University of Bucharest, Faculty of Physics, Atomiştilor 405, CP MG - 11, RO – 077125, Bucharest-Magurele, Romania

3) Polytechnic University of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Polizu Street, postal code 011061 or 132 Calea Grivitei, postal code 010737, sector 1, Bucharest, Romania


E-mail
chivuta_badita@yahoo.com


Keywords:
Chondroitin sulfate, hydrogels, small angle neutron scattering (SANS), scanning electron microscopy (SEM)


Abstract:
Chondroitin sulfate is a biological polymer important in the formation of cartilage and it is known to provide much resistance to compression. It can be used to construct high toughness gels. Due its anionic nature enables efficient interaction with cationic molecules to form interesting structure and it overall ability as a cell interacting molecules has spread its used in a variety of biomedical application [1, 2]. This paper provides a characterization and morphological properties of chondroitin sulfate hydrogels by Small-Angle Neutron Scattering (SANS) and Scanning Electron Microscopy (SEM) techniques. To characterize the morphology of chondroitin sulfate hydrogels the hierarchical Beaucage model was applied. This study may provide very useful insights for biomedical applications and the pharmaceutical industry.


References:

[1]. Reis, R. L., Neves, N. M., Mano, J. F., Gomes, M. E., Marques, A. P., & Azevedo, H. S. (2008). Natural-based polymers for biomedical applications. Elsevier.

[2]. Kwon, H. J., & Han, Y. (2016). Chondroitin sulfate-based biomaterials for tissue engineering. Turkish Journal of Biology, 40(2), 290-299.